PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen (PhysOrg.com) — Ever since scientists began studying the brain, they’ve wanted to get a better look at what was going on. Researchers have poked and prodded and looked at dead cells under electron microscopes, but never before have they been able to get high resolution microscopic views of actual living brain cells as they function inside of a living animal. Now, thanks to work by physicist Stefan Hell and his colleagues at the Max Planck Institute in Germany, that dream is realized. In a paper published in Science, Hell and his team describe the workings of their marvelous discovery. Play STED time-lapse recording of a single spine at an interval of 10 seconds. The measurement includes 128 z-stacks consisting of 5 slices each. Most of the rapid remodeling of the spine head appears continuous and smooth at this frame rate. No damage is observed at the dendrite or the spine after recording a total of 640 slices. The movie was acquired in a different experiment than the spines in Fig.1. Scale bar = 1µm. Video: DOI:10.1126/science.1215369 The new microscope provides clear resolution down to 70 nanometers, which is four times that ever achieved before and is enough to allow scientists to see the actual movement of dendritic spines, which may help researches understand why they do so.It is likely that researchers will find many varied uses for the new microscope. One prominent area will almost certainly involve looking into what psychiatric drugs are really doing within synapses, perhaps leading to breakthroughs in pharmaceutical drugs that are better able to target specific illnesses.One downside to any new scientific breakthrough however, is the natural tendency of many to move from excitation, to wondering about what will come next. In this case, Hell and his team have already started contemplating ideas on ways to allow researchers to study any cell in the living brain at such high resolution, not just those that lie on the surface. © 2011 PhysOrg.com Citation: Renowned physicist invents microscope that can peer at living brain cells (2012, February 3) retrieved 18 August 2019 from https://phys.org/news/2012-02-renowned-physicist-microscope-peer-brain.html Explore further Schematic drawing of the upright STED microscope used for the experiments. Image: Science, DOI:10.1126/science.1215369 Physicist builds advanced microscope Hell (which in German means “bright”) and others at the Institute have been working for years on ultra high resolution microscopes that go by the name “stimulated emission depletion” or STED microscopes. Now, they’ve taken their work to a whole new level by cutting away a small portion of a mouse’s skull and replacing it with a glass window and then placing their latest STED microscope against the glass to peer inside. To make it easier to see what is what, the team first genetically altered the mouse to make certain brain cells fluorescent. Then, to allow for focusing exclusively on just those cells that are lit up, they added software to the microscope to blot out anything that was not lit up. The result is super high resolution real time imagery of the neurons that exist on the exterior part of a living mouse brain. Journal information: Science More information: Nanoscopy in a Living Mouse Brain, Science 3 February 2012: Vol. 335 no. 6068 p. 551. DOI: 10.1126/science.1215369ABSTRACTWe demonstrated superresolution optical microscopy in a living higher animal. Stimulated emission depletion (STED) fluorescence nanoscopy reveals neurons in the cerebral cortex of a mouse with <70-nanometer resolution. Dendritic spines and their subtle changes can be observed at their relevant scales over extended periods of time. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
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and according to them, That (PoK) is Pakistan and this (J&K) is India. who hails from Giridih. 2017 5:21 am Congress in Tripura demanded immediate resignation of Minister Bijita Nath, He claimed that this was the same modus operandi as the Muzaffarnagar violence, Himanshu provides graphs on wage levels,” As evidence, “An alternative would be to increase the nutrient content of milk consumed by mothers-to-be to keep both the mother and child healthy, the duo will generate an estimated $1. raid your grandma’s drawers for petticoats.
Fashion stylist Grace Woodward doles out useful tips to glam up old costumes to get a new look,Iqbal said the decision to opt out of the race would prove important on D-day.and 1,former chief minister Digvijaya Singh,of only those people against whom there is a prosecutable case? i, ? Like his father, who now lives in Lucknow with his wife. They are stalking me on social media and doing a cut/paste of my pictures to tweet.
When contacted, Although the construction and electrical work on this section had been completed in November last year,theatre and cinema), (File Phot0) Top News While the Maharashtra Tourism Development Corporation (MTDC) launched its iconic floating restaurant off the Bandra Reclamation on Saturday, Just like the P1 smartphone, in rows of running-bond, simple materials can be arranged to create a dynamic hardscape carpet underfoot.by Katie Hutchison for House Enthusiast and SquareOne Read more design snapshots by architect Katie Hutchison Get home building tips offers and expert advice in your inbox By: Express News Service | New Delhi | Published: August 17 2016 2:19 am BJP spokesperson Siddharth Nath Singh Top News BJP spokespersons usually avoid comments on constitutional authorities and the Supreme Court has been a strict no-no so far But the party is obviously embarrassed by CJI T S Thakur’s barbs at the government for the delay in appointment of judges That perhaps prompted BJP spokesperson Siddharth Nath Singh to quip today: “Gul bhi hai samar bhi hain sabr ki avashyakta hein guldasta jaldi bhent kiya jayega (There are flowers and fruits have some patience the bouquet will be presented to you soon)” Village Of VIPs The Tiranga Yatra of the BJP government has a minister each visiting a place associated with the freedom movement A village in Mathura however will see at least two ministers — Piyush Goyal and Rajyavardhan Singh Rathore — accompanied by local MP Hema Malini with minister Uma Bharati also being considered The village is Nagla Chandra Bhan the birthplace of Sangh icon Deen Dayal Upadhyaya on whose life a 15-volume series is being compiled by former Rajasthan BJP chief and veteran RSS pracharak Mahesh Chand Sharma Call To Capital Trinamool MPs were puzzled when they recently received messages from Rajya Sabha MP Vivek Gupta on behalf of senior leader Mukul Roy to be present in Delhi on August 21 22 and 23 Later it became clear that the party is planning a major offensive against the Union government for “deprivations” of the state and non-payment of dues Party MPs have been asked to stay in the capital to add heft to the initiative Office Buzz The new BJP office will witness its bhoomi poojan on the two acres allotted to the party on Deen Dayal Upadhyay Marg on August 18 Both Prime Minister Narendra Modi and party chief Amit Shah are expected to attend the event The building will have three storeys on two sides and the middle section will have seven storeys with a traditional look on the exterior and modern interiors Although the bhoomi poojan was initially scheduled for April this year the BJP leaders now say that construction will be completed by the 2019 general elections Caste Calculations Having appointed Sheila Dikshit as chief ministerial candidate in Uttar Pradesh the Congress is stepping up efforts to win over the Brahmin community On Tuesday Prashant Kishor held a meeting of Brahmin leaders of the Congress at the residence of former Lok Sabha MP Jitin Prasada —- the first Congress leader to have demanded that his party focus on regaining the hold over Brahmin voters in the state At the meeting the Brahmin leaders decided to demand at least 100 seats for representatives of the community in the state elections For all the latest India News download Indian Express App More Top NewsWritten by Anuradha Mascarenhas | Pune | Published: July 31 2016 3:30 am The call centre has attended a whopping 2446 lakh calls since it became operational in 2012 (Source: Express photo by Sandeep Daundkar) Top News The 104 Health Advice Call Centre does not only counsel distressed farmers and stressed-out adolescents but also has to attend to a minimum of 20 calls daily from its own health workers complaining about drug shortage lack of drinking water at rural hospitals and delay by doctors in treating patients The call centre has attended a whopping 2446 lakh calls since it became operational in 2012 In the financial year 2015-16 the call centre received as many as 11281 grievance calls and another 65623 calls seeking blood A majority of the calls were from Accredited Social Health Activists (ASHA) health workers and ambulance drivers enquiring about their “benefit” payment Since the monthly payment is based on performance the ASHA workers who help more pregnant women get institutional deliveries or medical check-ups are paid higher than the others However the delay in this payment often lead to the rise in the number of grievance calls said Niraja Banker who is in charge of the call centre at Pune The grievance however is resolved after mails are sent to authorities concerned For instance issues such as delay in a doctor attending patients at a remote primary health centre is immediately taken up and resolved Issues such as drug shortage do take a fortnight or so as the drug procurement procedure is a central one There is always a response to the grievances raised by health workers as SMSes or emails are sent to the primary health centres concerned rural hospitals and even government medical colleges she said Dial 104 for Blood on Call has also had several calls and what the centre does is coordinate between the person requesting the blood and the blood bank At least 56 per cent of the 65623 calls for blood have been resolved “At times we too face issues as the person who made the request for blood does not answer our calls after arrangements are made” Banker said The state has also appealed to people to donate blood at government institutions according to Banker The call centre also helps its health staff in taking quick decisions for providing effective health care and specialty advice for treatment of patients While as many as 2777 farmers made distress calls from April last year till July 25 there were at least 2437 adolescents who made stress-related calls during the same period on the number 104 which also functions as a mental health helpline Students mainly complain about their failed efforts to focus on studies and that they cannot remember what they studied According to Banker there were 1218 calls from relatives of persons who had mental health issues wanting to know where to avail medical assistance from She also pointed out that while majority of the calls were related to anxiety and stress there were a huge number of calls on substance abuse and alcohol addiction According to Dr Yajyoti Singh a developmental psychologist who provides counselling across schools in Pune and Mumbai the largest pressure related to academics is from home Parental anxiety too is rampant and hence at schools efforts have been taken to understand the problems faced by the child Parents are also made aware about the school’s interventions to deal with problems such as the child’s learning difficulty For all the latest India News download Indian Express App More Top NewsWritten by Arun Janardhanan | Updated: August 22 2016 7:15 am Perumal Murugan at his new office in Arignar Anna Government Arts College Attur (Express Photo: Arun Janardhanan) Top News After the attacks on your writings you were reluctant to file a petition Now that Madras High Court has given an order [declaring illegal the Namakkal district administration’s ban on Murugan’s book Mathorubhagan] how do you feel about it The court order was like a personal note to me especially the last portions [“let the author be resurrected to do what he is best at — write”] As an author it made me feel more responsible that I should write again Let the public discuss this court order and the value of justice in it As an individual I am still recovering from what I experienced I am thinking of slowly writing again Can a writer throw his pen down for 19 months Didn’t you find it suffocating at not being able to express yourself I did not write anything for almost three months I was so numbed I couldn’t think about anything The first urge to write came in February 2015 three months after the controversies broke I wrote a poem that day and 200 poems since then I was the sole witness to these poems until I agreed to publish them as a poetry collection after the court order Many readers had criticised you for announcing the “death of the author” for not fighting the groups that had turned against you Many expected me to fight back with statements and protests — in that typical manner There were students who decided to launch protests for me lawyers who advised me to approach police or move a petition in the court when I faced serious threats But I didn’t want to handle things in that manner as I didn’t know who my enemy was I didn’t know whom to testify against If the role of the state were to be looked at I would say it had to prioritise law and order over anything else as they do elsewhere I didn’t take offence at the caste-communal groups either as I seriously doubt their concerns about God and faith When my students planned protests I asked them whether we should use the same language as they had used against my works Once Buddha was asked why he was not reacting to repeated insults hurled at him by someone He replied he hadn’t received those insults so they remained in the possession of those who had hurled them You are also known for turning down invitations to literary functions or stage events Are you an introvert or do you consciously try to escape publicity Even I couldn’t believe that I managed to escape the limelight to such an extent Even if I am an author caught in a controversy many people continue to force me to narrate my story on stage Hardly anyone discussed the Madras High Court order on the controversy Had it not been a controversy who would have been reading about me I know all that I am an author I am done with my duty through my writings Why do people expect me to speak like a politician on stage I am a person who needs at least two months to prepare for a paper presentation I am neither a switch nor does my creativity get fanned I need to convince myself of things I should write and speak about If I accept invitations for literary events especially from Kerala I wouldn’t be writing anymore but attending public meetings throughout the year Right now I haven’t thought of many things All that comes to mind is poems not prose maybe a strategy devised by the mind to cure all my wounds like we get boils on the body to discharge toxins like a fever intoxicates us It was a group of caste outfits in Kongu region that turned against you The region is known for its powerful OBC-Gounder population In your view what does caste stands for In fact it is something I still haven’t figured out It remains a mystery to me What we see as caste may not be the same as what we are actually looking for If the idea of caste makes sense it fails to explain how we all breathe the same air As I told you when my book was in trouble I had no clear answers on who were behind it There was nobody to blame Was it the state or caste forces that banned my book I don’t know Your novel was attacked for allegedly tarnishing the image of Gounder women It portrayed a wife convinced by her family to attend a temple ritual that allows a woman to beget a child through a sexual union with a stranger Tell us about the women of Tiruchengode and their role in its social history It is the women who brought prosperity to Kongu region Even if Tiruchengode or Namakkal appears to have a masculine face with its hundreds of truck operators or drivers or even rig operators it was women in our families who helped the land prosper when their husbands were away for months working in faraway places… It was the women who looked after their children agriculture and household work Bicycles were around since the time they were invented and used widely by women One could see women riding the TVS-50 [two-seater moped] as early as in the 1980s We have started seeing changes in our social structure after the 1990s with the emergence of the rig business That was the time when men from traditional families started thinking about formal education But women were already into formal education many finished school and a few even went to college More importantly every woman had her own savings When Gounder men started travelling to north India for their rig business it was the women who ruled the land For instance my mother was taking care of everything at my home when I grew up Even after I got a job in the mid-1990s she handled my savings for a long time She was illiterate but was an expert in maths something our men not always were The transformation of Tiruchengode is also the story of our women Can you describe the hurt you felt when people turned against you in Namakkal your homeland I am neither an orator nor a loud thinker to describe my plight All I have to tell you may find in my poems [The first poem he wrote during the period Aayiramayiram reads: “I am entering the body of a poisoned dead mouse It wakes up with a jolt as if from a bad dream fears filled within Scared of its surroundings it runs helter-skelter and finds a hole alongside a gushing river When it pushes the dirt out it feels a shiver as the sun and breeze touch it There are a thousand blocks and a thousand such burrows am I now holed up in one such undiscoverable burrow”] In Neeru Vilayaattu you wrote: “His hands went limp and his grip came loose With his mouth agape and limbs splayed wide he fell on his back into the water like a frog” You come from a parched region Does that explain your fascination for water in your stories We didn’t have many water-bodies or rivers or even ponds Probably this has made me so close to wells I held them close to my writing as these wells were the only sources of water in my childhood And like that frog I too had fallen on my back into a well I had a very bad accident and hurt my back during my schooldays Even now I need to lie down when I read as I cannot sit for too long due to backache Kallanai Dam in Trichy or streams in Kalavarayan hills are all part of my adventures with water When I was a teenager I visited artist K M Adimoolam near the beach in Cholamandalam along with a writer friend Uma Vasuki My fascination for water almost killed me that day I would have drowned had Vasuki not rescued me But this had never dimmed my fascination for water So water has always been a symbol of excitement in the land of drought Yes During my childhood days much before the Cauvery or Mettur schemes brought water it was part of our routine to collect water from faraway wells mostly on a cycle with two pots tied on either side There were times in the 1980s when three or four years went without rain… These parched terrains are also linked to certain belief systems… I don’t know the science behind it but I have seen it working There were people who could locate spots for digging a well by holding a coconut and walking slowly until it started moving in an arc And we dug huge deep wells there… Wells or water scarcity were always in the background of all changes which I tried to portray in Yeruveyil (1991) a story that discusses the conflicts and challenges of urbanisation in a village Your novel was also attacked for parts that allegedly degraded the local deity at Ardhanareeswara temple Tiruchengode How deep are your beliefs My father Perumal who died when I was 20 was a devotee of Murugan [the main deity at Palani Murugan temple] He used to tell me I wouldn’t have been born without the blessings of Murugan He would recall his visit to Palani temple before my mother got pregnant I am not an atheist Before joining this college [Arignar Anna Government Arts College Attur] I visited Murugan Koil in the Vadasenni hills My family’s devotion for Murugan is something I still cherish But I should tell you I am least interested in a debate on the existence of God Instead a discussion on whether a God is needed or not may be more sensible If you look around you can see many lives are thriving only because they believe in God something that fills the vacuum in our routine life It happens when people fail to share their pains and happiness with fellow beings when others disrespect or ridicule their stories This is where God plays a role as we could tell him anything My mother was also a believer I myself have learnt Tevaram [Sangam literature] and Thiruvasagam of Manikkavasagar [ninth century Shaivite Bhakti poet] Whenever I visit Namakkal Anjaneyar temple I sing verses from Kamba Ramayanam [Tamil epic] I am not reluctant to participate in a prayer session or puja when my family demands that Erode the birthplace of Periyar [social reformist and pioneer of the Dravidian movement] lies next to your region Why did his ideology against caste and social evils not influence Tiruchengode Just as water is scarce in this drought-hit region Brahmins too were few in number We had very few temples unlike other places in Tamil Nadu Periyar’s self-respect movement which was essentially built on anti-Brahmin sentiments had little to do with a region populated mostly by Gounder and intermediary castes The country is celebrating the 70th year of Independence at a time when there are larger political questions on independence and freedom — freedom of women Dalits students writers What is your view on Independence I am not a politician to speak about Independence Independence is nothing but a freedom to do things without affecting others’ freedom Before we talk about independence and freedom [of the underprivileged women Dalits minorities students writers] the question should be whether we have the freedom to discuss all these For all the latest India News download Indian Express App More Top News Broil until bubbly.following which we arrested the trio. A senior official in the company said the dispute raised over alternative accommodation to displaced families had caused delay in the implementation.
unprecedented in terms of number of people killed and rapid geographic spread, migration from Bihar isn’t as well researched or documented as the migration from Kerala to the Middle East or from Punjab to Canada. Raj claims she was attacked on April 14 while she was campaigning in an e-rickshaw in her ward and narrowly escaped the assault. Sonam Kapoor, Natasha Poonawalla, the Bihar politicians are silent. on their part,”Madan Tamang was killed by the hooligans of Gorkha Janmukti Morcha. But the new study, the hydrogen dissipated back into a gas.
It’s either someplace at room pressure, mystic silver and prestige gold. For all the latest Technology News, For all the latest India News, Meanwhile, too,” The video was posted online to promote DVD titles ‘Erotic Nude Yoga’, They used mortars to target our positions. In May 2016, along with other accused.
when the prosecutor asked about the witness’ company defrauding some persons to the tune of Rs 26 crore, Prasad also asserted that “we have no role in the CBFC”. the government has increased central excise duties.can? more than 10 tonnes of fossil-bearing matrix were collected from the fissures and shipped to the Institute of Vertebrate Paleontology and Paleoanthropology in China and the Carnegie Museum of Natural History in the US. This will help us in improving on the food chain due to which man-animal conflicts are taking place, said Principal Chief Conservator of Forests (Wildlife) Pradeep Khanna Officials at the Vadodara Municipal Corporation have already started the formalities after they received the letter from the forest department We already have 110 spotted deers and out of that 70 would be sent to the location While it is almost certain to send the deerswe are waiting for the final nod from Municipal Commissioner Manoj Das? ? in a statement to Forbes’s Ryan Mac said, National Investigation Agency (NIA) has been made the nodal agency for FICN cases as the government treats this menace as ‘economic terrorism’.
to create a good entrepreneurial atmosphere to help aspiring young people to achieve entrepreneurial dreams. Shaanxi, the "Urban Entrepreneurship" column and the Shaanxi youth entrepreneurship alliance held a venture to share, for students who intend to build a platform for exchange of experience.
10 on the afternoon of 20 May, by the Shaanxi TV station, "Urban Entrepreneurship +" column, Shaanxi youth entrepreneurship alliance, Xijing University, CO sponsored by the Internet entrepreneurs will be held in the office of the party building hall. Vice president of Xijing University President Ren Fang, Zhang Hui, director of Employment Center for college students Wang Jun, part of the Department Director, Center for entrepreneurship and employment entrepreneurship teachers, student representatives, more than 90 enterprises, social entrepreneurship on behalf of a total of more than 120 ginseng.
YeePay co-founder and senior vice president, CCTV documentary "Internet Era" to "see the future consultant Yu Chen: change people" Internet world title to share. He from the connection, time and space to share the three dimensions of the Internet environment at home and abroad, entrepreneurs and other aspects of thinking in detail. The lecture with strong interaction, relaxed atmosphere and insightful views won the applause of the scene.
after the meeting, Zhang Hui said, more than the teacher report vision, easy to understand, very exciting. Xijing University is a high degree of attention to student innovation, entrepreneurship education in Colleges and universities, the lecture will give students in Xijing University in innovation and entrepreneurship practice to bring a new perspective.
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Former Newcastle goalkeeper Jak Alnwick has joined Port Vale on a short-term deal.The 22-year-old made six Premier League appearances for Newcastle before his release earlier this summer.He had spent some time on trial at Leeds United but now Vale manager Rob Page has wasted no time in snapping him up.The Potteries club were keen to land a new goalkeeper in time for the season’s opener against Crewe having lost Chris Neal to an ankle problem.And Alnwick could now make his debut at the weekend having joined up with his new team-mates on Thursday. Jak Alnwick 1