The second contract awarded was for the replacement of seven overhead doors at the fire hall that had been in service for over 20 years and are deteriorating, causing heat loss and increased repair costs for the building. The contract was awarded to Dice Petroleum for just under $23,000.Lastly, a contract was awarded to complete the NAR (Northern Alberta Railways) Museum Foundation Stabilization Project. The project scope was divided into three stages with each stage encompassing roughly one third of the building, but due to the bids received for the project last year coming in to high only phase 2 and phase 3 were completed, leaving the east end of the building, where the museum and interpretive centre are located, incomplete. That phase of the project has been awarded to Hegge Construction, the firm responsible for completing the other two phases of the project, and the only company to bid on the last phase.Chute said with the exception of the Reclaimed Water Plant and truck fill station tender, the above mentioned tenders received only two, one or no bids.“This is unfortunately the environment we work in – we are lucky to get tenders for any of our work,” said Chute. “It has a negative, upward pressure on pricing when there are so few bidders.”Advertisement Mississauga-based firm Maple Reinders was the low bid received and was awarded the contract for the final phase of the Reclaimed Water Project – a joint initiative between the City of Dawson Creek and Shell Canada – at a cost of about $5.76 million. Under an agreement reached last year, Shell will reimburse the city for the cost of constructing the reclaimed water plant, while city taxpayers will cover the cost of building the truck fill station.The first phase of the Reclaimed Water Project involved the construction of three Submerged Attached Growth Reactors (SAGR) cells and associated facilities and site work. Chief administrative officer Jim Chute said the total project remains on budget and on time, providing the microbial community required for the SAGR cells is provided ample time and conditions to grow.In total, Shell will provide $9.75 million towards the cost of the project and the city will provide an estimated $1.5 million. In exchange, Shell retains the rights to the first 3,400 cubic metres per day of the reclaimed water over a 10-year period and the city has the rights to the next 1,100 cubic metres per day, with any additional product being evenly split between the two parties, with Shell paying for its share.- Advertisement -Council’s intent for the project was to reduce the demand from the oil and gas industry in the area on the city’s potable bulk water by offering the treated effluent as an alternative.Council also awarded two contracts related to fire protection in the city.The first was to upgrade a water supply line to a fire curtain – a structure designed to prevent fires from spreading to other buildings – inside the Memorial Arena in order to meet current BC Building Code standards. The tender for the work closed July 12 with no bids received, and as a result city staff secured a sole-source contract worth $35,500 from B3 Fire Protection. Staff reported that the bid meets the tender specifications and is within the project budget, and that the firm contracted id capable of completing all areas identified in the tender package.Advertisement
Source:https://www.iospress.nl/ Reviewed by James Ives, M.Psych. (Editor)Dec 18 2018Heart and lung complications are responsible for much of the morbidity and mortality associated with Duchenne muscular dystrophy (DMD). Although regular monitoring of pulmonary function is recommended in order to detect deterioration, compliance with routine testing, such as hospital-based spirometry, is frequently poor. A new study in the Journal of Neuromuscular Diseases describes the at-home use of a child-compatible, hand-held device (HHD) that makes monitoring pulmonary function in teens more convenient and provides the data needed for better disease management.”This is the first study that demonstrates that the use of a hand-held device to assess pulmonary function is feasible in adolescent patients with DMD. Pulmonary function data obtained by this method are reliable as shown by comparison to standard spirometry results and participating patients showed a high level of adherence in the use of the device. This new approach to collect pulmonary function data, together with several analyses methods, could be used in the planning of clinical intervention trials with respiratory function endpoints or to improve routine clinical care in patients with DMD,” explained Prof. Gunnar M. Buyse, MD, PhD, Department of Paediatric Neurology, University Hospitals Leuven (Belgium).DMD is a debilitating neuromuscular disease that is usually diagnosed in children between the ages of 3 and 5 years. During the early teenage years, patients with DMD find their mobility impaired and pulmonary function begins to deteriorate. Clinical symptoms include the inability to cough efficiently, poor airway clearance, recurrent respiratory infections and, eventually, respiratory failure necessitating ventilator support. “Safeguarding pulmonary function, therefore, represents a significant unmet need,” said Dr. Buyse.This study was part of a multinational, randomized, placebo-controlled Phase III study (DELOS) investigating whether the drug idebenone could improve or delay the loss of respiratory function in adolescents 10-18 years old with DMD. One aim of the trial was to compare assessment of pulmonary function with a hand-held device to spirometry performed in a clinic or hospital.Related StoriesStudy analyzes high capacity of A. baumannii to persist on various surfacesStudy explores role of iron in over 900 diseasesMultifaceted intervention for acute respiratory infection improves antibiotic-prescribingThe results showed that weekly use of the hand-held device was well accepted by adolescent trial participants over the course of a year, with average adherence exceeding 75%. Comparison of values for peak expiratory flow expressed as percent of predicted (PEF%p) collected with the hand-held device with data obtained on the same day with standard spirometry were highly correlated indicating the reliability of this method. Both assessment methods showed that idebenone treatment slowed the decline in pulmonary function compared to placebo.Explanations for the limited compliance to hospital-based pulmonary function testing could be that physicians do not recommend testing, or patients are not followed in specialized neuromuscular centers where pulmonary function tests are available and recommended. Use of a hand-held device would offer an appropriate addition to hospital-based spirometry assessment with the advantage of allowing more frequent collection of pulmonary function data. Another possibility is that teenagers with limited mobility may be resistant to traveling to clinical centers.Advantages of using home-based pulmonary function monitoring include the ability to obtain more frequent assessments, sometimes on a daily basis, which could facilitate early detection of pulmonary function decline. The study also showed that short observation periods (between 2 and 4 weeks) were sufficient to distinguish clinical changes in PEF%p. Finally, this method may prove to be very useful for clinical testing of new therapies for DMD.